近(jin)年(nian)來中(zhong)(zhong)(zhong)國醫(yi)藥(yao)(yao)領域，zui有影響力(li)的(de)事(shi)件顯然是(shi)屠呦呦獲得諾貝爾獎.把中(zhong)(zhong)(zhong)醫(yi)藥(yao)(yao)的(de)創新成果推向世界科(ke)技(ji)榮譽(yu)殿堂，也進一(yi)(yi)步激發(fa)了(le)國內外對(dui)中(zhong)(zhong)(zhong)醫(yi)藥(yao)(yao)的(de)興趣和熱情。如今國內外對(dui)中(zhong)(zhong)(zhong)醫(yi)藥(yao)(yao)寄予(yu)了(le)更(geng)多關注(zhu)和更(geng)大期待(dai)，更(geng)是(shi)掀起(qi)一(yi)(yi)股(gu)“掘金”中(zhong)(zhong)(zhong)醫(yi)藥(yao)(yao)的(de)熱潮。但是(shi)中(zhong)(zhong)(zhong)藥(yao)(yao)如何粉碎，粉碎到(dao)什么程度才能得到(dao)更(geng)高的(de)藥(yao)(yao)效，溶(rong)解度更(geng)高?

   中(zhong)藥(yao)(yao)粉(fen)(fen)碎(sui)(sui)(sui)主要是借機械力將大塊的固體藥(yao)(yao)材(cai)粉(fen)(fen)碎(sui)(sui)(sui)成(cheng)適(shi)宜程度(du)的碎(sui)(sui)(sui)塊或細粉(fen)(fen)的操作過(guo)程。也(ye)可借助其(qi)它方(fang)法(fa)將固體藥(yao)(yao)材(cai)碎(sui)(sui)(sui)成(cheng)微粉(fen)(fen)的程度(du)，如(ru)(ru)低(di)溫粉(fen)(fen)碎(sui)(sui)(sui)，就(jiu)是借助待粉(fen)(fen)碎(sui)(sui)(sui)物料在低(di)溫狀態下的境性，而(er)進行粉(fen)(fen)碎(sui)(sui)(sui)的一種(zhong)方(fang)法(fa)。中(zhong)藥(yao)(yao)粉(fen)(fen)碎(sui)(sui)(sui)的目主要是為了更好應用在中(zhong)藥(yao)(yao)生(sheng)物工程與(yu)(yu)制藥(yao)(yao)工程中(zhong)增加(jia)藥(yao)(yao)物的表面(mian)積，促進藥(yao)(yao)物的溶解與(yu)(yu)吸收，提(ti)高藥(yao)(yao)物的生(sheng)物利用度(du)便于適(shi)應多種(zhong)給藥(yao)(yao)途(tu)徑的應用，便于藥(yao)(yao)物中(zhong)有(you)效物質(zhi)的侵出(chu)或溶出(chu)，為制備各種(zhong)劑型(xing)提(ti)供原科，如(ru)(ru)散劑、沖劑、丸劑、片劑等劑型(xing)都褥用紉粉(fen)(fen)和顆粒成(cheng)型(xing)，也(ye)便于調劑和服用。

   據了解(jie)，現在(zai)zui重要(yao)應用(yong)領域(yu)就(jiu)是中(zhong)藥(yao)方面，隨著中(zhong)藥(yao)超微(wei)(wei)粉(fen)(fen)(fen)碎(sui)技(ji)術的不斷成熟(shu)，其在(zai)中(zhong)藥(yao)粉(fen)(fen)(fen)碎(sui)領域(yu)將(jiang)發揮著越(yue)來越(yue)重要(yao)的作用(yong)。河(he)北醫(yi)科(ke)大學(xue)做了一(yi)項研究，在(zai)銀(yin)杏(xing)葉(xie)的有(you)機(ji)溶劑(ji)提(ti)(ti)(ti)(ti)取(qu)(qu)工(gong)藝(yi)基礎上(shang)引入中(zhong)藥(yao)超微(wei)(wei)粉(fen)(fen)(fen)碎(sui)技(ji)術，考察了粉(fen)(fen)(fen)碎(sui)粒徑、溶劑(ji)用(yong)量和浸(jin)提(ti)(ti)(ti)(ti)時(shi)間(jian)對銀(yin)杏(xing)葉(xie)提(ti)(ti)(ti)(ti)取(qu)(qu)物(wu)(wu)得(de)率(lv)(lv)(lv)的影響。結果(guo)與對照工(gong)藝(yi)相比，將(jiang)銀(yin)杏(xing)葉(xie)粉(fen)(fen)(fen)碎(sui)至平均(jun)粒徑42μm左右時(shi)銀(yin)杏(xing)葉(xie)提(ti)(ti)(ti)(ti)取(qu)(qu)物(wu)(wu)中(zhong)黃酮苷的得(de)率(lv)(lv)(lv)從(cong)1.15%提(ti)(ti)(ti)(ti)高(gao)(gao)到(dao)了1.71%;銀(yin)杏(xing)內酯的得(de)率(lv)(lv)(lv)從(cong)0.47%提(ti)(ti)(ti)(ti)高(gao)(gao)到(dao)了 0.68%;溶劑(ji)用(yong)量節省了43%;浸(jin)提(ti)(ti)(ti)(ti)時(shi)間(jian)可(ke)選擇30 min，節省了75%。該結果(guo)表明(ming)，中(zhong)藥(yao)超微(wei)(wei)粉(fen)(fen)(fen)碎(sui)技(ji)術能有(you)效改善(shan)銀(yin)杏(xing)葉(xie)提(ti)(ti)(ti)(ti)取(qu)(qu)工(gong)藝(yi)。

   銀杏葉提(ti)取(qu)物(wu)應用中(zhong)(zhong)(zhong)藥(yao)(yao)超(chao)(chao)(chao)微(wei)技(ji)術(shu)后的(de)(de)(de)良好效果只是植物(wu)提(ti)取(qu)方面的(de)(de)(de)一(yi)(yi)個(ge)案例(li)，作(zuo)為粉(fen)碎(sui)機中(zhong)(zhong)(zhong)zui的(de)(de)(de)產(chan)品中(zhong)(zhong)(zhong)藥(yao)(yao)超(chao)(chao)(chao)微(wei)粉(fen)碎(sui)機的(de)(de)(de)優勢還有很(hen)多(duo)需要發(fa)掘。中(zhong)(zhong)(zhong)藥(yao)(yao)超(chao)(chao)(chao)微(wei)粉(fen)碎(sui)機的(de)(de)(de)發(fa)展(zhan)現(xian)(xian)在已經歷了許多(duo)年，從zui初的(de)(de)(de)仿制到現(xian)(xian)在的(de)(de)(de)創新研發(fa)，從單個(ge)行業到普(pu)及各個(ge)相關行業，中(zhong)(zhong)(zhong)藥(yao)(yao)超(chao)(chao)(chao)微(wei)粉(fen)碎(sui)機現(xian)(xian)在已經具(ju)備(bei)了非常強大的(de)(de)(de)粉(fen)碎(sui)能力(li)，經過中(zhong)(zhong)(zhong)藥(yao)(yao)超(chao)(chao)(chao)微(wei)粉(fen)碎(sui)后，中(zhong)(zhong)(zhong)藥(yao)(yao)可以達到輕松細胞壁破的(de)(de)(de)水平，這(zhe)個(ge)時(shi)候(hou)中(zhong)(zhong)(zhong)藥(yao)(yao)吸(xi)收率(lv)將會達到更大的(de)(de)(de)提(ti)高(gao)，對于(yu)這(zhe)個(ge)技(ji)術(shu)在珍貴中(zhong)(zhong)(zhong)藥(yao)(yao)的(de)(de)(de)利(li)用方面前景光明，對于(yu)保護(hu)中(zhong)(zhong)(zhong)藥(yao)(yao)品種(zhong)和提(ti)高(gao)利(li)用率(lv)有重(zhong)要意(yi)義，同樣的(de)(de)(de)對于(yu)植物(wu)提(ti)取(qu)物(wu)行業來說也(ye)是提(ti)高(gao)生產(chan)效率(lv)降低生產(chan)成本的(de)(de)(de)一(yi)(yi)個(ge)好的(de)(de)(de)方法。

   當前中藥(yao)(yao)超微(wei)粉碎(sui)機研究(jiu)以(yi)單味藥(yao)(yao)較多，主要圍繞(rao)是否提(ti)高溶出率、提(ti)高生物利用(yong)度、減(jian)少用(yong)藥(yao)(yao)量(liang)、增強藥(yao)(yao)理作用(yong)等方面(mian)進行。據悉(xi)，重壓研磨式超微(wei)粉碎(sui)機YSC-701成現代(dai)技(ji)術(shu)的(de)機械，科技(ji)含(han)量(liang)高對粉碎(sui)纖(xian)維性物料如靈芝，甘草，水牛角等效果(guo)明(ming)顯。這也(ye)為完善(shan)中藥(yao)(yao)的(de)應用(yong)和開(kai)發新(xin)型中藥(yao)(yao)制劑提(ti)供了設備(bei)上的(de)支持。

   中(zhong)藥超微粉是(shi)(shi)(shi)中(zhong)藥粗粉的延(yan)伸，但是(shi)(shi)(shi)不(bu)同(tong)(tong)于其他行業的超微粉體(ti)，其在粉碎中(zhong)藥時應(ying)注意多方面的事(shi)項。如(ru)中(zhong)藥的用藥部位(wei)復(fu)雜，包(bao)括花(hua)、葉(xie)、根、莖(jing)、全株等多種(zhong)(zhong)部位(wei)，各(ge)種(zhong)(zhong)不(bu)同(tong)(tong)部位(wei)間性(xing)(xing)質(zhi)(zhi)(zhi)差異很大，從細(xi)(xi)(xi)胞(bao)(bao)層面，其由外(wai)(wai)到內的各(ge)層，例(li)如(ru)木(mu)栓層、皮層、韌皮部、形成(cheng)(cheng)層、木(mu)質(zhi)(zhi)(zhi)部、射線(xian)等由不(bu)同(tong)(tong)種(zhong)(zhong)類細(xi)(xi)(xi)胞(bao)(bao)構成(cheng)(cheng)，其構成(cheng)(cheng)細(xi)(xi)(xi)胞(bao)(bao)如(ru)薄壁細(xi)(xi)(xi)胞(bao)(bao)、石細(xi)(xi)(xi)胞(bao)(bao)、導管、木(mu)纖(xian)維、木(mu)栓細(xi)(xi)(xi)胞(bao)(bao)等破壁性(xing)(xing)能是(shi)(shi)(shi)不(bu)同(tong)(tong)的。又如(ru)不(bu)同(tong)(tong)品種(zhong)(zhong)中(zhong)藥材(cai)性(xing)(xing)質(zhi)(zhi)(zhi)是(shi)(shi)(shi)不(bu)同(tong)(tong)的，如(ru)三七質(zhi)(zhi)(zhi)硬，黃精(jing)質(zhi)(zhi)(zhi)軟而(er)黏，黃芪纖(xian)維性(xing)(xing)強等。三七之外(wai)(wai)的其他品種(zhong)(zhong)中(zhong)藥超微粉的均勻(yun)性(xing)(xing)如(ru)何(he)，還需(xu)要從不(bu)同(tong)(tong)超微粉碎技術(shu)、評(ping)價(jia)指標、按不(bu)同(tong)(tong)性(xing)(xing)質(zhi)(zhi)(zhi)藥材(cai)進一步研究。

   中(zhong)藥(yao)粉碎機(ji)在中(zhong)藥(yao)加工扮演著(zhu)重要的角色，在制(zhi)藥(yao)機(ji)械市(shi)場也上廣受(shou)青睞。但是目(mu)前(qian)日益激烈的市(shi)場競(jing)爭(zheng)使得中(zhong)藥(yao)粉碎機(ji)行業的發展(zhan)(zhan)前(qian)景出(chu)現了(le)很大的變化(hua)。中(zhong)藥(yao)粉碎機(ji)生產企(qi)業要想在市(shi)場競(jing)爭(zheng)中(zhong)贏(ying)得一(yi)席之地(di)，就必須抓住行業發展(zhan)(zhan)方向(xiang)(xiang)。如隨著(zhu)智(zhi)(zhi)能化(hua)時代來襲，中(zhong)藥(yao)粉碎機(ji)也正在向(xiang)(xiang)智(zhi)(zhi)能化(hua)方向(xiang)(xiang)轉變，越來越多的智(zhi)(zhi)能產品將(jiang)涌現。